       Document 0300
 DOCN  M9610300
 TI    Human immunodeficiency virus-associated glomerulosclerosis.
 DT    9601
 AU    Humphreys MH; San Francisco General Hospital, University of California
       San; Francisco 94143, USA.
 SO    Kidney Int. 1995 Aug;48(2):311-20. Unique Identifier : AIDSLINE
       MED/96047704
 AB    The constellation of nephrotic proteinuria, FSGS, and rapid loss of
       renal function in a patient infected with HIV-1 has been sufficiently
       widespread and well documented to justify identification as a specific
       renal syndrome, HIV-associated nephropathy. The position paper of the
       National Kidney Foundation-National Institutes of Health task force
       estimated in 1990 that 10,000 to 15,000 persons will develop renal
       disease in association with AIDS [94]. Management of these patients is
       complex, and many will reach ESRD and require dialysis treatment, posing
       additional care problems. Greater understanding of the pathogenesis of
       the renal disease should lead to treatments which will forestall the
       development of HIVAN and possibly other forms of fibrotic renal disease.
       The ultimate eradication of AIDS will consign this renal syndrome to an
       interesting footnote in the history of nephrology. Since that time is
       still far in the future, nephrologists will continue to be faced with
       the need to diagnose and treat HIV-1-infected patients with renal
       involvement.
 DE    *AIDS-Associated Nephropathy/EPIDEMIOLOGY/PATHOLOGY/THERAPY  Biopsy
       *Glomerulosclerosis, Focal  Human  Kidney/PATHOLOGY  Kidney Failure,
       Chronic/THERAPY  JOURNAL ARTICLE  REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

