       Document 0270
 DOCN  M9610270
 TI    Bacteriology of sinusitis in human immunodeficiency virus-positive
       patients: implications for management.
 DT    9601
 AU    Upadhyay S; Marks SC; Arden RL; Crane LR; Cohn AM; Department of
       Otolaryngology-Head and Neck Surgery, Harper; Hospital, Wayne State
       University, Detroit, MI 48201, USA.
 SO    Laryngoscope. 1995 Oct;105(10):1058-60. Unique Identifier : AIDSLINE
       MED/96008488
 AB    The bacteriology of sinusitis in human immunodeficiency virus
       (HIV)-infected patients has been only sporadically reported. In this
       study, we report the results of cultures taken from 12 HIV patients with
       refractory chronic sinusitis who underwent surgery. Nine of the 12
       patients had positive cultures with 16 isolates and 5 patients having
       multiple isolates. Five of the 12 patients grew out atypical or
       opportunistic infections not responsive to standard medical therapy,
       including 3 patients with cytomegalovirus, 1 with Aspergillus fumigatus,
       and 1 with Mycobacterium kansasii. These results suggest the need for
       aggressive medical care for HIV-infected patients with sinusitis and
       early intervention for tissue cultures in patients who do not respond to
       standard antibiotic regimens.
 DE    AIDS-Related Opportunistic Infections/MICROBIOLOGY  Bacteria,
       Aerobic/ISOLATION & PURIF  Bacteria, Anaerobic/ISOLATION & PURIF
       Chronic Disease  Drug Resistance, Microbial  Drug Resistance, Multiple
       Human  HIV Seropositivity/*MICROBIOLOGY  HIV-1/*IMMUNOLOGY
       Sinusitis/*MICROBIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

