       Document 0210
 DOCN  M9610210
 TI    [Induced expectoration: its role in the diagnosis of pneumocystis
       carinii pneumonia]
 DT    9601
 AU    Cabie A; Mendoza-Sassi G; Matheron S; Dombret MC; Coulaud JP; Service
       des Maladies infectieuses et tropicales, Hopital Bichat,; Claude
       Bernard, Paris.
 SO    Presse Med. 1995 Jul 1-8;24(24):1119-20. Unique Identifier : AIDSLINE
       MED/96006414
 AB    OBJECTIVES: The purpose of this retrospective study was to describe the
       changes and the effect of Pneumocystis carinii pneumonia (PCP)
       prophylaxis on induced sputum sensitivity during these five last years
       METHODS: An induced sputum examination was performed in 80 cases of PCP
       over a 5-year period. RESULTS: The induced sputum were positive in 30
       cases (sensitivity = 37.5%). This sensitivity changed very little during
       these five years. Thirty of these 80 patients (37.5%) received PCP
       prophylaxis at least for four weeks before PCP diagnosis. Induced sputum
       sensitivity was 50% in the group with prophylaxis versus 30% in the
       group without prophylaxis (p = 0.073). CONCLUSION: In our institution,
       the induced sputum examination remains an interesting diagnostic
       procedure for PCP. PCP prophylaxis does not seem to have effects on
       induced sputum sensitivity.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS  Aerosols
       AIDS-Related Opportunistic Infections/COMPLICATIONS/*DIAGNOSIS/
       MICROBIOLOGY/PREVENTION & CONTROL  Bronchoalveolar Lavage
       Fluid/*MICROBIOLOGY  English Abstract  Human  Pentamidine/THERAPEUTIC
       USE  Pneumonia, Pneumocystis carinii/COMPLICATIONS/*DIAGNOSIS/
       MICROBIOLOGY/PREVENTION & CONTROL  Retrospective Studies  Saline
       Solution, Hypertonic/PHARMACOLOGY  Sputum/DRUG EFFECTS/*MICROBIOLOGY
       JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

