       Document 0185
 DOCN  M9610185
 TI    Unusual lymphoproliferative disorders in nine adults with HIV or AIDS:
       CT and pathologic findings.
 DT    9601
 AU    McGuinness G; Scholes JV; Jagirdar JS; Lubat E; Leitman BS; Bhalla M;
       McCauley DI; Garay SM; Naidich DP; Department of Radiology, New York
       University Medical Center, NY; 10016, USA.
 SO    Radiology. 1995 Oct;197(1):59-65. Unique Identifier : AIDSLINE
       MED/96023124
 AB    PURPOSE: To identify characteristic computed tomographic (CT) findings
       in unusual pulmonary lymphoproliferative disorders seen in adults with
       the human immunodeficiency virus (HIV) or acquired immunodeficiency
       syndrome (AIDS). MATERIALS AND METHODS: The authors retrospectively
       reviewed the CT scans and pathologic specimens from nine patients with
       pulmonary lymphoproliferative disorders. CT scans were evaluated for
       nodules, reticulation, areas of ground-glass attenuation, consolidation,
       and bronchial disease. Changes seen in pathologic specimens were
       classified as consistent with classic lymphocytic interstitial
       pneumonitis (LIP), mucosa-associated lymphoid tissue lymphoma (MALTOMA),
       or atypical lymphoproliferative disorder (ALD). Immunopathologic results
       were reviewed when available. RESULTS: Eight patients had AIDS. Five
       patients had classic LIP. One patient had MALTOMA, and three patients
       had ALD. Altogether, 2-4-mm-diameter nodules were the predominant CT
       finding in eight patients; these were peribronchovascular in four
       patients. The presence of interstitial nodules correlated with the
       pathologic finding of nodular disease in seven patients. CONCLUSION:
       Familiarity with these AIDS-related disorders and their CT appearance
       should assist in the differential diagnosis.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS/PATHOLOGY/
       RADIOGRAPHY  Adult  Female  Human  HIV
       Infections/*COMPLICATIONS/PATHOLOGY/RADIOGRAPHY  Lung Diseases,
       Interstitial/COMPLICATIONS/PATHOLOGY/RADIOGRAPHY  Lymphoma,
       Mucosa-Associated Lymphoid Tissue/COMPLICATIONS/  PATHOLOGY/RADIOGRAPHY
       Lymphoproliferative Disorders/*COMPLICATIONS/PATHOLOGY/  *RADIOGRAPHY
       Male  Middle Age  Retrospective Studies  Tomography, X-Ray Computed
       JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

