       Document 0162
 DOCN  M9610162
 TI    [Seroprevalence of HTLV-I in relatives of patients with spastic
       paraparesis (HAM/TSP and PEP)]
 DT    9601
 AU    Cartier L; Vergara C; Ramirez E; Casivar T; Vasquez A; Departamento de
       Ciencias Neurologicas, Facultad de Medicina,; Universidad de Chile,
       Santiago de Chile.
 SO    Rev Med Chil. 1995 Jan;123(1):7-11. Unique Identifier : AIDSLINE
       MED/96054114
 AB    The seroprevalence of HTLV-1 was studied in parents, brothers, siblings
       and sexual partners of 147 patients with spastic paraparesis associated
       to HTLV-1 (HAM/TSP) and 84 patients with HTLV-1 negative spastic
       paraparesis (SP). Seroprevalence was 29.1% for HAM/SP and 0% for SP
       relatives (p < 0.001); the last figure is similar to that of the general
       population. Seroprevalence in sexual partners was 65%, suggesting that
       sexual intercourse is the principal route of transmission. Likewise,
       seroprevalence in siblings of mothers with HAM/TSP or HTLV-1 positive
       was 17.6%, suggesting a high maternal transmission.
 DE    Adolescence  Adult  Aged  Aged, 80 and over  Analysis of Variance
       Chi-Square Distribution  Child  Child, Preschool  Comparative Study
       Cross-Sectional Studies  English Abstract  Family Health  Female  Human
       HTLV-I Infections/*EPIDEMIOLOGY/GENETICS/IMMUNOLOGY/TRANSMISSION  Infant
       Male  Middle Age  Paraparesis, Tropical
       Spastic/*EPIDEMIOLOGY/GENETICS/IMMUNOLOGY/  TRANSMISSION  Prevalence
       Seroepidemiologic Methods  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

