       Document 0155
 DOCN  M9610155
 TI    Usefulness of the detection of Toxoplasma gondii antigens in AIDS
       patients.
 DT    9601
 AU    Fachado A; Fonte L; Alberti E; Hadad P; Fonseca L; Machin R; Finlay C;
       Department of Parasitology, Institute of Tropical Medicine, Pedro;
       Kouri, Havana City, Cuba.
 SO    Rev Inst Med Trop Sao Paulo. 1994 Nov-Dec;36(6):525-9. Unique Identifier
       : AIDSLINE MED/96015890
 AB    Toxoplasmic encephalitis (TE) is a mayor cause of central nervous system
       infection in patients with acquired immunodeficiency syndrome (AIDS).
       Toxoplasma antibodies were detected in 56 of 79 patients with AIDS
       (71%), in the present study. Fourteen out of 57 seropositive patients
       developed TF (25%) and had Toxoplasma gondii antigen detected in their
       urine. For this, most of them received an effective therapy, with the
       subsequent disappearance of the symptoms and discontinuity of excretion
       of the T. gondii antigens. Our results suggest that the monitoring of T.
       gondii antigen in the urine of AIDS patients may be useful to decide on
       the proper time for therapy, as well as to avoid the beginning of
       neurologic signs in these patients.
 DE    Agglutination Tests  Animal  Antibodies, Protozoan/BLOOD  Antigens,
       Protozoan/*URINE  AIDS-Related Opportunistic
       Infections/COMPLICATIONS/*DIAGNOSIS/  URINE
       Encephalitis/COMPLICATIONS/DIAGNOSIS/*PARASITOLOGY/URINE  Enzyme-Linked
       Immunosorbent Assay  Fluorescent Antibody Technique  Human  Mice
       Rabbits  Toxoplasma/*IMMUNOLOGY  Toxoplasmosis,
       Cerebral/COMPLICATIONS/*DIAGNOSIS/URINE  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

