       Document 0151
 DOCN  M9610151
 TI    [Risks and regulations related to materials used in implantology and
       maxillofacial surgery]
 DT    9601
 AU    Rocher P; Veron C; Vert M; Chanavaz M; Donazzan M; Hildebrand HF;
       Laboratoire de Biophysique, Faculte de Medecine, Universite de; Lille
       II.
 SO    Rev Stomatol Chir Maxillofac. 1995;96(4):281-92. Unique Identifier :
       AIDSLINE MED/96000819
 AB    In the present paper, the authors call in mind the definitions of
       biocompatibility and the essential qualities required for biomaterials.
       The materials mostly used in implantology and maxillofacial surgery are
       numerous alloys, bioceramics, resorbable and non-resorbable polymers,
       and finally osseous substitutes of human or animal origin. As to
       synthetic and non-living materials, the risks in patients are generated
       by the degradation products. These may induce tissular reactions of
       inflammatory or immune origin owing to toxic effects. Concerning osseous
       substitutes, rejections are mostly of immune origin, for allografts and
       in particular for xenografts. Infections may be another major risk and
       in spite of all precautionary measures viral infections by hepatitis B,
       HIV and transmissible spongiform encephalopathy are not yet got under
       total control. It is just in these domains that one can state juristic
       lacks which national and european organisation of standardisation and
       homologation have to cover during the next few years.
 DE    Alloys/CHEMISTRY/STANDARDS  Animal  Bacterial Infections/PREVENTION &
       CONTROL  *Biocompatible Materials/CHEMISTRY/STANDARDS  Bone
       Substitutes/CHEMISTRY/STANDARDS  Bone Transplantation/STANDARDS
       Carcinogens  Ceramics/CHEMISTRY/STANDARDS  *Dental Implants/STANDARDS
       English Abstract  Europe  Face/*SURGERY  France  Human  *Implants,
       Artificial/STANDARDS  Jaw/*SURGERY  Legislation  Membranes, Artificial
       Polymers/CHEMISTRY/STANDARDS  Reference Standards  Risk Factors  JOURNAL
       ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

