       Document 0125
 DOCN  M9610125
 TI    [Blood transmission and infections]
 DT    9601
 AU    Eggen BM; Avdeling for immunologi og blodbank, Regionsykehuset i
       Trondheim.
 SO    Tidsskr Nor Laegeforen. 1995 Oct 10;115(24):3035-8. Unique Identifier :
       AIDSLINE MED/96038697
 AB    A blood transfusion can never become a completely risk free event.
       Almost all kinds of infectious agents; viruses, bacteria and parasites,
       can be transmitted by blood. So far, hepatitis and HIV-infections have
       been focused. The state of readiness to meet these infections must be
       kept while we prepare for new agents, like parvovirus B19. Extensive
       international travelling will increase the possibility of blood-borne
       parasitic infections, like malaria and Chagas' disease, even with the
       very high quality demands imposed for Norwegian blood donors. We can
       keep a better eye on the infectivity of the blood products by strictly
       realizing our objective of national self-sufficiency. Recent research
       results indicate transfusion-mediated effects to the immune system,
       particularly of allogeneic transfusions containing leucocytes. This
       immunomodulation seems to enhance the risk of secondary infections. So
       far, it is impossible to tell whether this immunomodulation has any
       impact on the long-term outcome of malignant diseases. A blood
       transfusion will always represent a risk, although small, to the
       patient. This recognition makes it essential to carefully consider
       whether to give a patient a transfusion, and to document this decision
       properly.
 DE    Blood Transfusion/*ADVERSE EFFECTS/STANDARDS  *Blood-Borne Pathogens
       English Abstract  Human  Norway  *Quality Assurance, Health Care  Risk
       Factors  JOURNAL ARTICLE  REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

