       Document 0119
 DOCN  M9610119
 TI    Recruitment to a trial of tuberculosis preventive therapy from a
       voluntary HIV testing centre in Lusaka: relevance to implementation.
 DT    9601
 AU    Godfrey-Faussett P; Baggaley R; Mwinga A; Hosp M; Porter J; Luo N; Kelly
       M; Msiska R; McAdam K; Department of Medicine, University Teaching
       Hospital, Lusaka,; Zambia.
 SO    Trans R Soc Trop Med Hyg. 1995 Jul-Aug;89(4):354-8. Unique Identifier :
       AIDSLINE MED/96014710
 AB    To determine the number of clients attending for voluntary human
       immunodeficiency virus (HIV) testing who are able to enter a trial of
       preventive therapy for tuberculosis, and the factors that determine who
       receives therapy, we studied 475 consecutive people attending for an HIV
       test at Lusaka's first voluntary HIV testing centre and the preventive
       therapy study clinic at the University Teaching Hospital, Lusaka,
       Zambia. Semi-structured interviews were conducted by counsellors and
       collated with recruitment data from the trial. Two hundred and
       twenty-five people were seropositive, of whom 201 returned to collect
       their results; 77 (38%) of these (16% of the total number screened)
       entered the trial. Reasons for not entering the trial included exclusion
       by trial protocol (30), including 18 who had active tuberculosis;
       psychological adjustment to a positive result (27); death (6); worries
       about confidentiality (3); the experimental nature of the trial (12);
       attitudes of staff in the hospital (5); and cost of transport (7).
       Targeting preventive therapy at those who are already choosing to be
       tested for HIV seems appropriate and may be cost-effective. Although
       visiting a hospital may deter some people, the prevalence of active
       tuberculosis among this group emphasized the importance of arranging
       adequate screening facilities.
 DE    AIDS Serodiagnosis  AIDS-Related Opportunistic Infections/*COMPLICATIONS
       Clinical Trials  Human  Patient Acceptance of Health Care  *Patient
       Selection  Referral and Consultation  Support, Non-U.S. Gov't
       Tuberculosis/COMPLICATIONS/DIAGNOSIS/*PREVENTION & CONTROL  Zambia
       JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

