       Document 0062
 DOCN  M9610062
 TI    The AIDS epidemic in India: a new method for estimating current human
       immunodeficiency virus (HIV) incidence rates.
 DT    9601
 AU    Brookmeyer R; Quinn T; Shepherd M; Mehendale S; Rodrigues J; Bollinger
       R; Department of Biostatistics, School of Hygiene and Public Health,;
       Johns Hopkins University, Baltimore, MD 21205, USA.
 SO    Am J Epidemiol. 1995 Oct 1;142(7):709-13. Unique Identifier : AIDSLINE
       MED/96009972
 AB    Human immunodeficiency virus (HIV) incidence rates in India were
       estimated using a new method that accounts for follow-up bias. Follow-up
       bias arises in epidemiologic cohort studies when the incidence rate
       among individuals who do and do not return for follow-up are different.
       The new method combines data on the prevalence of p24 antigenemia among
       all those initially screened together with the longitudinal follow-up
       data on the subset of patients who returned for follow-up. Using these
       methods, the current HIV incidence rate among patients attending
       sexually transmitted disease clinics in Pune, India, was 18.6% per year.
       It was found that follow-up bias can cause significant underestimation
       in HIV incidence rates, perhaps by as much as 60%. These incidence
       estimates, together with other HIV seroprevalence studies, suggest the
       HIV epidemic in India is growing rapidly.
 DE    Acquired Immunodeficiency Syndrome/EPIDEMIOLOGY  Bias (Epidemiology)
       Confidence Intervals  Cross-Sectional Studies  Data Interpretation,
       Statistical  Female  Follow-Up Studies  Human  HIV
       Infections/BLOOD/COMPLICATIONS/*EPIDEMIOLOGY  HIV Seroprevalence
       Incidence  India/EPIDEMIOLOGY  Male  Seroepidemiologic Methods  Sexually
       Transmitted Diseases/COMPLICATIONS  Support, U.S. Gov't, P.H.S.  JOURNAL
       ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

