      Document 0053
 DOCN  DRG0053
 UNIQUE IDENTIFIER        DRG-0194
 NAME OF SUBSTANCE        Glutamic acid hydrochloride [Facts and
                          Comparisons 1995]
 REGISTRY NUMBER          138-15-8
 STANDARD CHEMICAL NAME   L-glutamic acid, hydrochloride [CHEMLINE]
 SYNONYMS                 Feracid [NIAID ACTG 183]
 SYNONYMS                 Acidulin [Merck Index 1989]
 SYNONYMS                 Acidoride [Merck Index 1989]
 SYNONYMS                 Hypochylin [Merck Index 1989]
 SYNONYMS                 Antalka [Merck Index 1989]
 SYNONYMS                 Aciglumin [Merck Index 1989]
 SYNONYMS                 Pepsdol [Merck Index 1989]
 SYNONYMS                 Glutamidin [Merck Index 1989]
 SYNONYMS                 Acidogen [Merck Index 1989]
 PROTOCOL ID NUMBERS      NIAID ACTG 183
 SECONDARY SOURCE ID      DRG
 DISEASES STUDIED/TREATED Prevention of hypochlorhydria, in order to
                          enhance absorption of oral ganciclovir [NIAID
                          ACTG 183]
 CLASSIFICATION CODE      Gastric acidifier [Facts and Comparisons
                          1995]
 OTHER MAJOR USES         Gastric acidifier [Facts and Comparisons
                          1995]
 CHEMICAL/PHYSICAL DATA   MOLECULAR FORMULA: C5H10ClNO4 [Merck Index
                          1989]
 CHEMICAL/PHYSICAL DATA   MOLECULAR WEIGHT:  183.59 [Lancaster 1992]
 CHEMICAL/PHYSICAL DATA   MELTING POINT:     214 F [Lancaster 1992]
 SUBSTANCE DELIVERY DATA  DOSAGE FORM: 340 mg. [NIAID ACTG 183] [Facts
                          and Comparisons 1995]
 SUBSTANCE DELIVERY DATA  MODE OF DELIVERY: Oral. [NIAID ACTG 183]
 MANUFACTURERS            Major Pharmaceuticals Inc
 REFERENCES               Russell TL, Berardi RR, Barnett JL,
                          O'Sullivan TL, Wagner JG, Dressman JB.
                          pH-related changes in the absorption of
                          dipyridamole in the elderly. Pharm Res. 1994
                          Jan;11(1):136-43.
 REFERENCES               Carver PL, Berardi RR, Knapp MJ, Rider JM,
                          Kauffman CA, Bradley SF, Atassi M. In vivo
                          interaction of ketoconazole and sucralfate in
                          healthy volunteers. Antimicrob Agents
                          Chemother. 1994 Feb;38(2):326-9.
 REFERENCES               Knapp MJ, Berardi RR, Dressman JB, Rider JM,
                          Carver PL. Modification of gastric pH with
                          oral glutamic acid hydrochloride. Clin Pharm.
                          1991 Nov;(11):866-9.
 ENTRY MONTH              9402
 LAST REVISION DATE       951027
 

SOURCE: National Library of Medicine, Bethesda, MD.  Distributed by AEGIS.
