       Document 0940
 DOCN  M9440940
 TI    AIDS dementia complex and HIV-1 infection: a view from the clinic.
 DT    9404
 AU    Price RW; Sidtis JJ; Brew BJ; Department of Neurology, University of
       Minnesota, Minneapolis; 55455-0323.
 SO    Brain Pathol. 1991 Apr;1(3):155-62. Unique Identifier : AIDSLINE
       MED/94122947
 AB    The AIDS dementia complex (ADC) is a clinical syndrome which
       characteristically presents as a subcortical dementia with cognitive,
       motor and behavioral changes. While the pathogenesis remains puzzling in
       a number of critical aspects, ADC likely relates in a fundamental way to
       HIV-1, itself, rather than to a secondary, opportunistic condition. This
       review focuses on some of the clinical information which bears on the
       pathogenesis of this syndrome and its relation to HIV-1 infection. This
       information derives from studies of the clinical character of ADC, its
       epidemiology and natural history, cerebrospinal fluid analysis,
       neuroimaging results, clinical correlates of pathological findings and
       its response to antiviral therapy.
 DE    Antiviral Agents/THERAPEUTIC USE  *AIDS Dementia Complex/CEREBROSPINAL
       FLUID/DRUG THERAPY/  EPIDEMIOLOGY/ETIOLOGY/PATHOLOGY/PSYCHOLOGY  Human
       *HIV-1  Support, U.S. Gov't, P.H.S.  JOURNAL ARTICLE  REVIEW  REVIEW,
       TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

