       Document 0837
 DOCN  M9440837
 TI    Total reaction time: a new approach in early HIV encephalopathy?
 DT    9404
 AU    Dunlop O; Bjorklund R; Abdelnoor M; Myrvang B; Department of Infectious
       Diseases, Ullevaal University Hospital,; Oslo, Norway.
 SO    Acta Neurol Scand. 1993 Nov;88(5):344-8. Unique Identifier : AIDSLINE
       MED/94127155
 AB    In an attempt to develop better methods for diagnosis, screening and
       serial assessment of HIV-1-associated cognitive/motor complex, we have
       added a motor component to tests of reaction time, defining the new
       parameter as total reaction time. Thirty-four non-drug-using,
       HIV-positive men underwent four different tests of total reaction time.
       All four tests reached a level of statistical significance, both for a
       group of patients with early disease and for a group of patients with
       symptoms, compared with a control group. Total reaction time had a
       better discriminatory ability than standard reaction time, particularly
       for patients with early disease. It is suggested that neuropsychological
       studies of HIV-1-associated cognitive/motor complex should include tests
       of total reaction time.
 DE    Adult  Auditory Perception/PHYSIOLOGY  AIDS Dementia
       Complex/CLASSIFICATION/*DIAGNOSIS/PHYSIOPATHOLOGY  Choice
       Behavior/PHYSIOLOGY  Human  *HIV-1  Male  Middle Age  Motor
       Neurons/PHYSIOLOGY  Neurologic Examination  Psychomotor
       Performance/*PHYSIOLOGY  Reaction Time/*PHYSIOLOGY  Reference Values
       Support, Non-U.S. Gov't  Visual Perception/PHYSIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

