       Document 0804
 DOCN  M9440804
 TI    Kaposi's sarcoma in Italy before and after the AIDS epidemic.
 DT    9404
 AU    Geddes M; Franceschi S; Barchielli A; Falcini F; Carli S; Cocconi G;
       Conti E; Crosignani P; Gafa L; Giarelli L; et al; Servizio di
       Epidemiologia Descrittiva, Valutativa e di; Cancerogenesi Ambientale,
       Sezione dell'IST di Genova, Italy.
 SO    Br J Cancer. 1994 Feb;69(2):333-6. Unique Identifier : AIDSLINE
       MED/94128529
 AB    The incidence of Kaposi's sarcoma (KS) in 1976-90 was assessed in Italy,
       taking advantage of a network of nine population-based cancer registries
       covering, at its maximum, approximately 5.6 million subjects. The first
       examined period (1976-84) substantially reflects the epidemiology of KS
       prior to the AIDS epidemic in the registration areas. Elevated incidence
       rates, standardised to the Italian population of 1981, of 1.05/100,000
       men and 0.27/100,000 women emerged in 1976-84 (i.e. from two- to
       threefold higher than in the USA and Sweden, more than tenfold higher
       than in England and Wales). These high rates, especially remarkable in
       the Registry from the south of Italy (i.e. Ragusa, 3.01/100,000 men and
       0.54/100,000 women) suggest that the prevalence of the still unknown
       causative agent for KS was high, at least in some parts of Italy, prior
       to the AIDS epidemic. In the most recent period (1985-90), an
       approximately twofold increase in KS incidence rates in Italian men
       below age 50 was observed (from 0.15 in 1976-84 to 0.47 in 1985-90).
       Conversely, declines in KS incidence were recorded in older men.
 DE    Acquired Immunodeficiency Syndrome/*EPIDEMIOLOGY  Female  Human
       Incidence  Italy/EPIDEMIOLOGY  Male  Registries  Sarcoma,
       Kaposi's/*EPIDEMIOLOGY  Sex Distribution  Support, Non-U.S. Gov't
       JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

