       Document 0476
 DOCN  M9440476
 TI    Coxiella burnetii infection among subjects infected with HIV type 1 in
       the Central African Republic.
 DT    9404
 AU    Belec L; Gresenguet G; Ekala MT; Jacob A; Vohito MD; Cotigny S; Payan C;
       Laboratoire de Microbiologie, Hopital Broussais, Paris, France.
 SO    Eur J Clin Microbiol Infect Dis. 1993 Oct;12(10):775-8. Unique
       Identifier : AIDSLINE MED/94139767
 AB    Sixty-six sera from HIV-1-seropositive adult African subjects and 49
       sera from HIV-seronegative age and sex matched healthy African controls
       living in Bangui, Central African Republic, were screened for Coxiella
       burnetii antibody by an indirect immunofluorescent antibody test. 16.7%
       of HIV-infected patients and 16.3% of the HIV-negative controls had
       positive IgG titres, with no significant difference between the two
       groups. Two of the seven HIV-infected patients seropositive for Coxiella
       burnetii for whom clinical data was available had a medical history
       compatible with symptomatic Q fever. These findings indicate that there
       is a high degree of exposure to Coxiella burnetii infection in Bangui.
       In individuals co-infected with HIV and Coxiella burnetii, cellular
       immunosuppression could favour symptomatic Q fever. Physicians should be
       aware of the possibility of symptomatic Coxiella burnetii infection
       among HIV-infected people, particularly in endemic regions for both
       infections such as in sub-saharan Africa.
 DE    Adult  Africa, Central/EPIDEMIOLOGY  AIDS-Related Opportunistic
       Infections/*EPIDEMIOLOGY  Female  Human  *HIV-1  Male  Prevalence  Q
       Fever/*EPIDEMIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

