       Document 0259
 DOCN  M9440259
 TI    The impact of HIV and other STDs on human populations. Are predictions
       possible?
 DT    9404
 AU    Boily MC; Brunham RC; Department of Medical Microbiology, University of
       Manitoba,; Winnipeg, Canada.
 SO    Infect Dis Clin North Am. 1993 Dec;7(4):771-92. Unique Identifier :
       AIDSLINE MED/94149263
 AB    This article presents an overview of the use of mathematical models to
       study the demographic impact of STDs. Written for the nonmathematician,
       the article introduces the basic concepts of mathematical epidemiology
       for infectious diseases, such as the mass-action principle, the
       threshold density concept, and the basic reproductive rate. Described
       are the main features that characterize the epidemiology of STDs and
       those features that differentiate them from other directly transmitted
       diseases, such as measles, rubella, and others. Also presented are major
       findings concerning the importance of sexual behavior on the dynamics of
       STD transmission, and the numerical analysis of the demographic impact
       on gonococcal and HIV infections using a mathematical model. The
       epidemiology of these two STDs is explored, as well as how the growth
       rate of the population can influence the epidemiology of these STDs.
       Finally, the authors demonstrate how, under some circumstances, early
       treatment of gonorrhea can reduce the demographic impact of HIV in
       regions most affected by both diseases.
 DE    Female  Gonorrhea/*EPIDEMIOLOGY  Human  HIV Infections/*EPIDEMIOLOGY
       Male  *Models, Theoretical  Sex Behavior  Sexually Transmitted
       Diseases/*EPIDEMIOLOGY  Support, Non-U.S. Gov't  JOURNAL ARTICLE  REVIEW
       REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

