       Document 1024
 DOCN  M9541024
 TI    Phylogenesis and genetic complexity of the nonhuman primate
       retroviridae.
 DT    9504
 AU    Franchini G; Reitz MS Jr; Laboratory of Tumor Cell Biology, National
       Cancer Institute,; National Institutes of Health, Bethesda, Maryland
       20892.
 SO    AIDS Res Hum Retroviruses. 1994 Sep;10(9):1047-60. Unique Identifier :
       AIDSLINE MED/95127286
 AB    The three known groups of nonhuman primate retroviruses (simian
       immunodeficiency virus, simian T cell lymphotropic/leukemic virus type
       I, and simian foamy virus) are thought to have equivalent human
       counterparts. This is clearly the case with human immunodeficiency virus
       types 1 and 2, the causative agents of acquired immunodeficiency
       syndrome, and with human T cell lymphotropic/leukemia virus type I
       (HTLV-I), which causes T cell leukemia and a progressive form of
       myelopathy (tropical spastic paraparesis/HTLV-I-associated myelopathy),
       and HTLV-II. However, the presence of spumaviruses (foamy viruses) in
       humans remains uncertain. Data accumulated in the last 5 years suggest
       the possibility that the human retroviruses are indeed the result of
       transmission of simian retroviruses to humans. In this article we
       attempt to parallel the genetic features of the simian retroviridae with
       their human counterparts and argue for the possibility of horizontal
       transmission of these viruses from monkeys to humans.
 DE    Animal  Comparative Study  Genes, Regulator  Genes, Viral
       Hominidae/VIROLOGY  Human  *Phylogeny  Primates/*VIROLOGY
       Retroviridae/*CLASSIFICATION/*GENETICS  SIV/CLASSIFICATION/GENETICS
       STLV/GENETICS  JOURNAL ARTICLE  REVIEW  REVIEW, ACADEMIC

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

