       Document 1005
 DOCN  M9541005
 TI    Preliminary results of HIV screening in sentinel facilities in Romania.
 DT    9504
 AU    Cernescu C; Popescu A; Tirdei G; Alexandrescu R; Ruta SM; Stefan S.
       Nicolau Institute of Virology, Bucharest, Romania.
 SO    Rev Roum Virol. 1993 Jul-Dec;44(3-4):171-3. Unique Identifier : AIDSLINE
       MED/95127473
 AB    In the first months of 1994, 393 patients (random consecutive clinic
       attenders) from three sentinel clinics were tested for anti-V3 loop
       antibodies in ELISA with a branched synthetic peptide reproducing eight
       copies of full V3 sequence. Compared with a commercial HIV 1/2 ELISA kit
       the sensitivity of anti-V3 assay was 97.6% and the specificity 89.7%.
       The seroprevalence in women attending prenatal clinic was 7.54% and in
       children with multiple hospitalization record, 3.82%. Both heterosexual
       and parenteral transmission through unsafe medical practices fuel actual
       AIDS epidemic in Romania.
 DE    Adult  Child  Comparative Study  Enzyme-Linked Immunosorbent Assay
       False Negative Reactions  False Positive Reactions  Female  Human  HIV
       Antibodies/BLOOD  HIV Envelope Protein gp120/GENETICS  HIV
       Seropositivity/*DIAGNOSIS/EPIDEMIOLOGY  HIV Seroprevalence
       HIV-1/*IMMUNOLOGY  Molecular Sequence Data  Romania/EPIDEMIOLOGY
       Sensitivity and Specificity  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

