       Document 0662
 DOCN  M95A0662
 TI    Aspirin study stopped. 
 DT    9510
 SO    Treat Rev. 1995 Mar/Apr;(no 17):4. Unique Identifier : AIDSLINE
       AIDS/95700321
 AB    A study using high-dose aspirin treatment for HIV infection was stopped
       due to side effects, including reduction in red blood cells and a modest
       increase in liver enzymes. When treatment stopped, lab values returned
       to normal. Material strongly cautioning people about trying aspirin on
       their own was released in connection to the study. A related drug,
       salasalate, is being tested in a clinical trial as well, but it is still
       not known whether it is safe or effective for treatment of HIV disease.
       The Community Research Initiative has other studies that are enrolling,
       such as one using U-90, also known as delavirdine. Results from this
       drug appear promising.
 DE    Anemia/*CHEMICALLY INDUCED  Aspirin/*ADVERSE EFFECTS/THERAPEUTIC USE
       HIV Infections/*DRUG THERAPY  Human  Liver/ENZYMOLOGY  NEWSLETTER
       ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

