       Document 0650
 DOCN  M95A0650
 TI    Measles immunity in HIV-infected children.
 DT    9510
 AU    Walter EB; Katz SL; Bellini WJ; Department of Pediatrics, Duke
       University Medical Center, Durham,; North Carolina, USA.
 SO    Pediatr AIDS HIV Infect. 1994 Oct;5(5):300-4. Unique Identifier :
       AIDSLINE AIDS/95330394
 AB    In a retrospective study, sera from 84 children of human
       immunodeficiency virus (HIV)-seropositive mothers (35 HIV-infected and
       49 uninfected children) with a known date of receipt of measles, mumps,
       and rubella vaccine were tested for antibody to measles vaccine by an
       indirect enzyme immunoassay (EIA) method and/or microneutralization
       (NEUT). At the time of last measurement, 21/35 (60.0%) HIV-infected
       children remained seropositive by either EIA or NEUT. Forty seven of
       forty-nine (95.9%) uninfected children had evidence of measles antibody.
       Six HIV-infected children had a documented loss of antibody over time.
       The majority of HIV-infected children had antibody to measles vaccine
       virus, which in some cases decreased over time.
 DE    Antibodies, Viral/*ANALYSIS  Human  HIV Infections/*IMMUNOLOGY
       Immunization  Immunoenzyme Techniques  Infant  Measles
       Vaccine/*IMMUNOLOGY  Measles Virus/IMMUNOLOGY  Mumps Vaccine/IMMUNOLOGY
       Neutralization Tests  Retrospective Studies  Rubella Vaccine/IMMUNOLOGY
       Support, Non-U.S. Gov't  Support, U.S. Gov't, P.H.S.  Vaccines,
       Combined/IMMUNOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

