       Document 0696
 DOCN  M94A0696
 TI    HIV-related mycobacterial infections in Queensland.
 DT    9412
 AU    Konstantinos A; Dawson D; Patel AM; Mycobacterial Reference Laboratory,
       Queensland Health, Brisbane.
 SO    Annu Conf Australas Soc HIV Med. 1993 Oct 28-30;5:33 (abstract no. FC3).
       Unique Identifier : AIDSLINE ASHM5/94348959
 AB    Human Immunodeficiency Virus (HIV) related mycobacterial infections in
       Queensland (Qld) were studied to define which mycobacteria contribute to
       HIV-related disease in Qld and implications for management. Mycobacteria
       were isolated from 112 HIV patients in Qld from 1/7/85-22/1/93
       (Mycobacterium tuberculosis complex [MTBC] in 7 and atypical
       mycobacteria [ATM] in 105). 94 of 108 ATM isolates in the latter were
       M.avium complex (MAC) (75 M.avium and 19 M.intracellulare) with
       different serotypes often isolated from different sites in the same
       patient. HIV associated MTBC infection is not yet a problem in Qld. As
       most non HIV-related MAC infections Qld in the past were
       M.intracellulare, the predominance of M.avium infections in this study
       suggests that either HIV patients are particularly susceptible to
       M.avium infection, or there has been a recent shift in the mycobacterial
       population as supported by a recent increase in M.avium isolates from
       lymph nodes in non HIV-infected Qld children. Further evaluation of the
       role of different MAC serotypes in significant disease requires
       prospective study.
 DE    Adult  AIDS-Related Opportunistic Infections/DIAGNOSIS/*EPIDEMIOLOGY
       Child  Cross-Sectional Studies  Human  Incidence  Mycobacterium
       avium-intracellulare Infection/DIAGNOSIS/  *EPIDEMIOLOGY
       Queensland/EPIDEMIOLOGY  Tuberculosis, Pulmonary/DIAGNOSIS/*EPIDEMIOLOGY
       MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

