       Document 0792
 DOCN  M9550792
 TI    [African histoplasmosis: clinical and therapeutic aspects, relation to
       AIDS. Apropos of 4 cases, including a case with HIV-1-HTLV-1
       co-infection]
 DT    9505
 AU    Geffray L; Veyssier P; Cevallos R; Beaud B; Mayolle J; Nogier C; Ray E;
       Thouvenot D; Service de Medecine Interne et Maladies Infectieuses,
       Centre; Hospitalier de Compiegne, Compiegne.
 SO    Ann Med Interne (Paris). 1994;145(6):424-8. Unique Identifier : AIDSLINE
       MED/95168732
 AB    The authors report 4 cases of African histoplasmosis in Zairans. The
       diagnostic was based ou cutaneous (4 patients), bones (3), lymph-nodes
       (2), and bowel-localizations (1) and was confirmed by the presence of
       Histoplasma duboisiis yeasts in cutaneous biopsy (4 patients), in pus of
       abscess or cutaneous lesions (3) and in stools (1). Two HIV
       seronegatives patients had a good outcome with amphotericin B. One
       patient died without any treatment. One HIV-1 and HTLV-1 seropositive
       patient had successful short-term outcome with ketoconazole. Seven
       others cases of association between African histoplasmosis and AIDS are
       noted in the literature. They suggest the opportunistic nature of this
       deep mycosis.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS/MICROBIOLOGY  Adult
       *AIDS-Related Opportunistic Infections  Case Report  English Abstract
       Female  *Histoplasmosis/DIAGNOSIS/THERAPY  Human  HIV
       Infections/COMPLICATIONS/MICROBIOLOGY  *HIV-1  *HTLV-I
       Infections/COMPLICATIONS  Male  Zaire  JOURNAL ARTICLE  REVIEW  REVIEW
       OF REPORTED CASES

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

