       Document 0667
 DOCN  M9550667
 TI    Cutaneous cryptococcosis with molluscum contagiosum coinfection in a
       patient with acquired immunodeficiency syndrome.
 DT    9505
 AU    Sulica RL; Kelly J; Berberian BJ; Glaun R; Division of Dermatology,
       Georgetown University Medical Center,; Washington, DC 20007.
 SO    Cutis. 1994 Feb;53(2):88-90. Unique Identifier : AIDSLINE MED/95154023
 AB    We report the first patient with acquired immunodeficiency syndrome in
       whom molluscum contagiosum and Cryptococcus neoformans were documented
       in the same cutaneous lesion. While cases of the co-occurrence of two
       pathologic entities in patients with acquired immunodeficiency syndrome
       have been reported, namely cytomegalovirus with herpes simplex virus and
       Kaposi's sarcoma with Histoplasma capsulatum, the findings in this
       patient are unique. The clinical presentation of cutaneous lesions
       caused by molluscum contagiosum and by Cryptococcus neoformans is
       reviewed. The findings in this case are more remarkable still given the
       often-noted tendency of cutaneous cryptococcosis to masquerade as
       molluscum contagiosum. It may be that the lesions of molluscum
       contagiosum create a favorable environment for cryptococcal
       dissemination. Examination of a biopsy specimen is crucial to the
       diagnosis of skin lesions, often atypical or deceptive, in
       immunosuppressed patients.
 DE    Adult  AIDS-Related Opportunistic Infections/*COMPLICATIONS/PATHOLOGY
       Case Report  Cryptococcosis/*COMPLICATIONS/PATHOLOGY
       Dermatomycoses/*COMPLICATIONS/PATHOLOGY  Diagnosis, Differential  Human
       Male  Molluscum Contagiosum/*COMPLICATIONS/PATHOLOGY  JOURNAL ARTICLE
       REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

