       Document 0483
 DOCN  M9550483
 TI    [Immune system indices for the prediction of the course of human
       immunodeficiency virus infection]
 DT    9505
 AU    Gabrilovich DI; Serebrovskaia LV; Khabarova VV; Kravchenko AV; Avdeeva
       LA; Shalygina NB; Pokrovskii VV
 SO    Zh Mikrobiol Epidemiol Immunobiol. 1994 Aug-Sep;Suppl 1:114-8. Unique
       Identifier : AIDSLINE MED/95159695
 AB    In 25 persons having HIV infection with different dynamics of the
       progress of the disease the content of lymphocyte populations was
       studied (by the methods of rosette formation and with the use of
       monoclonal antibodies) and the rosette-forming and functional metabolic
       activity of neutrophils was determined. In comparison with patients with
       a stable course of HIV, patients with relatively rapid progress
       infection were found to have a significantly lesser amount of
       E-rosette-forming cells (E-RFC), active E-RFC, theophylline resistant
       E-RFC, E-rosette-forming neutrophils (E-RFN) and active E-RFN in
       combination with a significantly higher neutrophil and phosphatase
       activity and a significantly higher content of cation proteins. These
       characteristics may be used as criteria for prognosis of HIV infection
       progression.
 DE    Adult  Analysis of Variance  B-Lymphocytes/ENZYMOLOGY/IMMUNOLOGY
       Comparative Study  Disease Progression  English Abstract  Female  Human
       HIV Infections/*IMMUNOLOGY  *HIV-1  Lymphocyte Count  Male
       Neutrophils/ENZYMOLOGY/IMMUNOLOGY  Prognosis  Rosette Formation
       T-Lymphocytes/ENZYMOLOGY/IMMUNOLOGY  Time Factors  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

