                     AIDS Daily Summary 
                      October 25, 1994

The Centers for Disease Control and Prevention (CDC) National AIDS
Clearinghouse makes available the following information as a public
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Copyright 1994, Information, Inc., Bethesda, MD


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"'Doe's' Boss Tells of Job Critiques"
"German AIDS-Detecting Drug Recalled; Maker Says It Missed Virus 
in One Case"
"Japan Admits Failed to Warn Over HIV-Tainted Blood"
"French, U.S. Officials Plan AIDS Meeting"
"U.S.-Ivory Coast AIDS Project Targets Women"
"Michael Douglas and Chayanne to Join Sharon Stone and Other 
Superstars Presenting Culinary Delights at "The Big Feast on the 
Beach""
"Risperidone in HIV-Related Manic Psychosis"
"The Content of Ethical Problems Experienced by Persons with 
AIDS"
"New Blood Charges in Paris"
"Armed and Dangerous"
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"'Doe's' Boss Tells of Job Critiques"
Philadelphia Inquirer (10/25/94) P. B1;  Slobodzian, Joseph A.
     Steven Asher, "Scott Doe's" former boss, testified before a 
federal jury yesterday that he often criticized the lawyer--who 
has AIDS--for being a poor writer and researcher.  The lawyer 
claimed he had to rewrite Doe's briefs and other work so 
extensively that once when he gave Doe an assignment, Doe 
replied, "Why should I bother, you're only going to rewrite it 
anyhow."  Asher also referred to a note he had written in the 
fall of 1992 that said, "The honeymoon year is over.  The 
banker's hours must cease."  Asher said that he has no copies of 
that memo or of any of Doe's first draft to prove his allegations
of poor work habits that led to Doe's dismissal from the firm in 
March 1993.  Doe contends that he was fired because of his 
HIV-positive status, and that Kohn, Nast & Graf violated the 
federal Americans with Disabilities Act, in addition to federal 
and state civil rights laws.  The case is the first suit 
involving HIV or AIDS to go to trial since the ADA took effect 
two years ago.  Dianne Nast, one of the name shareholders of the 
firm, also testified Monday and said that neither she nor the 
other directors at the firm knew that Doe had HIV until after he 
had sued them.
      
"German AIDS-Detecting Drug Recalled; Maker Says It Missed Virus 
in One Case"
Boston Globe (10/24/94) P. 52
     Hoechst, one of Germany's largest drug companies, has initiated a
recall of Enzygnost--a drug used for HIV testing--because it 
missed HIV in one instance.  Behring, the distributor of 
Enzygnost and a subsidiary of Hoechst, began a worldwide recall 
action to 35 countries on Oct. 15.  German pharmaceutical 
authorities have withdrawn the license for the drug.  In Japan, 
the Health and Welfare Ministry has requested more information so
it can decide whether people who previously tested negative with 
Enzygnost should be tested again.  It is believed that enough 
Enzygnost to test 150,000 people has been distributed in 
Japan--and 80 percent of that has already been used.  Behring 
spokesman Wolfgang Faust said that extensive retesting would not 
be necessary--only one problem case has occurred since the drug 
was introduced in 1991.  The diagnostic failure was partially 
explained by the gap between when a person is infected with HIV 
and when it can be detected in the blood, up to 12 weeks.  Faust 
said that Behring has applied to license a new, improved AIDS 
test drug and that Enzygnost had become obsolete.
      
"Japan Admits Failed to Warn Over HIV-Tainted Blood"
Reuters (10/24/94)
     Japan admitted on Monday that its Health Ministry in 1983 did not
publicize information it had about the risk of HIV contamination 
in imported blood products.  Documents--filed in a lawsuit 
against the government and two pharmaceutical companies by 
hemophiliacs who claim they were infected with HIV through 
tainted U.S. blood products--include the government's admission. 
The Japanese government had previously claimed it was not aware 
of a serious danger at the time.  The plaintiffs allege that if 
the information had been released it could have prevented an 
increase in HIV-infection among hemophiliacs.  The Health 
Ministry said that "in 1983, AIDS was not yet detected in Japan 
and nothing was known about its causes."
      
"French, U.S. Officials Plan AIDS Meeting"
Reuters (10/24/94)
     Health and Human Services Secretary Donna Shalala and French 
Social Affairs and Health Minister Simone Veil met Monday to plan
an international AIDS conference to be held in Paris.  The 
meeting went smoothly, despite research tensions between French 
and U.S. scientists.  "AIDS doesn't know if its French or 
American," said Shalala.  The December meeting will bring 
together high government officials from approximately 40 
countries to plot a concerted strategy to fight HIV.
      
"U.S.-Ivory Coast AIDS Project Targets Women"
Reuters (10/23/94)
     An AIDS project in Ivory Coast--funded by the U.S. Centers for 
Disease Control and Prevention--is trying to help the increasing 
number of women becoming infected with HIV.  Project Retro-CI 
will try to keep women seronegative for HIV and keep seropositive
women from developing opportunistic illnesses.  Ivory Coast has 
the highest reported rate of HIV-infection in west Africa.  
Retro-CI is working with the national AIDS committee and the 
Ivorian Health Ministry to determine what HIV information should 
be included in prenatal care, and whether it is possible to 
counsel and test all pregnant women for HIV.  A total of 3.3 
percent of Ivory Coast women tested HIV-positive in 1986; the 
figure is now greater than 16 percent.
      
"Michael Douglas and Chayanne to Join Sharon Stone and Other 
Superstars Presenting Culinary Delights at "The Big Feast on the 
Beach""
Business Wire (10/20/94)
     The list of celebrity chefs scheduled for "The Big Feast on the 
Beach" includes actor Michael Douglas and Latin pop star 
Chayanne.  The event--which will benefit the March of Dimes, 
Lend-A-Hand, and the United Foundation for AIDS--will focus on 
celebrities, stars, chefs, famed wine makers, and a line-up of 
great music.  Other celebrities who will attend the Big Feast on 
Nov. 4, 5, and 6 in Miami Beach, Fla., include actress Shari 
Belafonte, author Carl Hiaasen, and rocker Alice Cooper.
      
"Risperidone in HIV-Related Manic Psychosis"
Lancet (10/08/94) Vol. 344, No. 8928, P. 1029;  Singh, A. N.;  
Catalan, J.
     Manic psychosis is fairly common among people in the advanced 
stages of HIV.  Singh and Catalan successfully administered 
risperidone to four male psychotic AIDS patients with manic 
symptoms.  Following the Young mania rating scale, ratings in 
three patients fell from 43 to 8, 35 to 14, and 30 to 3 within 
seven to 10 days of receiving the drug.  In contrast to the study
by Dwight et al concluding that risperidone may exacerbate manic 
symptoms in patients with schizoaffective disorders, the 
preliminary findings of Singh and Catalan indicate that 
risperidone may be safe and effective in the treatment of 
AIDS-related psychosis with manic symptoms.
      
"The Content of Ethical Problems Experienced by Persons with 
AIDS"
Journal of the Association of Nurses in AIDS Care (9/94-10/94) 
Vol. 5, No. 5, P. 32;  Cameron, Miriam E.;  Crisham, Patricia;  
Lewis, Douglas E.
     Persons living with AIDS experience ethical problems that can 
significantly affect their health, families, healthcare 
personnel, and society.  A study was conducted to determine the 
foundations and contents of the problems in 25 people with AIDS 
and five significant others.   Totals of 45 and 17 different 
ethical concerns dealing with subjects such as death, alcohol and
drugs, discrimination, and finances emerged in the PWAs and 
significant others, respectively.  Ethical listening--actively 
and selectively focusing on a person's ethical dilemma, instead 
of other areas, such as medications or treatments--proved to be a
useful intervention in PWAs because the person was encouraged to 
articulate the problem and his or her feelings to someone who 
cared.  The findings also offered insight into the subject matter
of a wide-range of ethical problems experienced by PWAs.
      
"New Blood Charges in Paris"
Science (10/14/94) Vol. 266, No. 5183, P. 222
     Cell biologist Francois Gros--a former scientific counselor to 
the prime ministry and one of France's most well-known 
scientists--and physician Claude Weisselberg--a former adviser to
the health ministry--were added to the list of those accused in 
the contaminated blood scandal.  Several scientists and 
politicians have already been charged with "complicity in 
poisoning" for their roles in allowing the French blood supply to
go untested for HIV.  During May and June of 1985, the French 
government allegedly kept an U.S.-manufactured HIV antibody test 
off the market until it had developed its own version.  A special
magistrate will conduct an investigation to evaluate the charges 
and decide whether the accused should go to trial.
      
"Armed and Dangerous"
Advocate (10/18/94) No. 666, P. 28;  Morales, Jorge
     On Sept. 1, 62-year-old retired state worker William Lewis walked
into the offices of Frances Tarlton, a spokeswoman on AIDS issues
for the New York state health department, and slashed her throat 
with a linoleum knife.  Lewis, who called himself "an activist in
the fight against AIDS," has been charged with attempted murder, 
assault, burglary, and illegal possession of a weapon.  His 
answering machine had played a message informing callers that the
use of condoms "will force the evolution of an AIDS virus which 
can be spread through sneezing.  All humanity could be infected 
before we even know it is happening."  Lewis claimed that he 
attacked Tarlton--who survived the injury--to draw attention to 
his unorthodox theories about AIDS.  While state officials were 
quick to tighten security at the health department, AIDS groups 
did little to change their existing security measures.  AIDS 
organizations say that accessibility for patients is their main 
concern.  "It's important to us that our clients not feel like 
they're entering a maximum-security prison," said Ron Silverio, 
director of AIDS Community Services in Buffalo.
      
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