       Document 0069
 DOCN  M9460069
 TI    Viral persistence of simian type D retrovirus (SRV-2/W) in naturally
       infected pigtailed macaques (Macaca nemestrina).
 DT    9408
 AU    Moazed TC; Thouless ME; Department of Pathobiology, School of Public
       Health, University; of Washington, Seattle 98195.
 SO    J Med Primatol. 1993 Sep-Oct;22(7-8):382-9. Unique Identifier : AIDSLINE
       MED/94223669
 AB    To elucidate sites of SRV-2/W persistence, tissue DNA from three groups
       of naturally infected Macaca nemestrina was analyzed for provirus:
       vertically transmitted, viremic, seronegative macaques; horizontally
       transmitted, viremic, seronegative macaques, and nonviremic seropositive
       macaques. In viremic animals infected vertically, provirus was found in
       many tissues, whereas in those infected horizontally, proviral DNA was
       limited. In V-Ab+ macaques, provirus was detected in bone marrow and/or
       ileocecal junction, confirming the presence of provirus in V-Ab+
       animals.
 DE    Animal  DNA, Viral/ANALYSIS  Female  Macaca nemestrina/*MICROBIOLOGY
       Male  Monkey Diseases/EPIDEMIOLOGY/*MICROBIOLOGY  Prevalence
       Proviruses/ISOLATION & PURIF  Retroviridae
       Infections/EPIDEMIOLOGY/MICROBIOLOGY/*VETERINARY  Retroviruses Type D,
       Simian/GENETICS/IMMUNOLOGY/*ISOLATION &  PURIF  Seroepidemiologic
       Methods  Simian Acquired Immunodeficiency Syndrome/EPIDEMIOLOGY
       Support, U.S. Gov't, P.H.S.  Tumor Virus
       Infections/EPIDEMIOLOGY/MICROBIOLOGY/*VETERINARY
       Viremia/MICROBIOLOGY/VETERINARY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

