       Document 0021
 DOCN  M9460021
 TI    Application and accuracy of molecular phylogenies.
 DT    9408
 AU    Hillis DM; Huelsenbeck JP; Cunningham CW; Department of Zoology,
       University of Texas, Austin 78712.
 SO    Science. 1994 Apr 29;264(5159):671-7. Unique Identifier : AIDSLINE
       MED/94225204
 AB    Molecular investigations of evolutionary history are being used to study
       subjects as diverse as the epidemiology of acquired immune deficiency
       syndrome and the origin of life. These studies depend on accurate
       estimates of phylogeny. The performance of methods of phylogenetic
       analysis can be assessed by numerical simulation studies and by the
       experimental evolution of organisms in controlled laboratory situations.
       Both kinds of assessment indicate that existing methods are effective at
       estimating phylogenies over a wide range of evolutionary conditions,
       especially if information about substitution bias is used to provide
       differential weightings for character transformations.
 DE    Bacteriophage T7/*GENETICS  Computer Simulation  Dentists  Disease
       Transmission, Professional-to-Patient  Evolution  Female  *Genome, Viral
       Human  HIV/*GENETICS  HIV Envelope Protein gp120/GENETICS  HIV
       Infections/MICROBIOLOGY/TRANSMISSION  Male  Models, Biological
       *Phylogeny  Probability  Support, U.S. Gov't, Non-P.H.S.  JOURNAL
       ARTICLE  REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

