       Document 0848
 DOCN  M9460848
 TI    Acquired immunodeficiency syndrome--a review and update. History,
       characteristics of human immunodeficiency virus infection, its
       replication, biologic factors, and pathogenicity.
 DT    9404
 AU    Fox NW; McArthur CP; Department of Oral Biology, University of
       Missouri-Kansas City.
 SO    Arch Fam Med. 1993 Oct;2(10):1068-77. Unique Identifier : AIDSLINE
       MED/94154868
 AB    The search to find a cure for acquired immunodeficiency syndrome has led
       to an unprecedented explosion of knowledge about viruses in general,
       especially retroviruses, of which the human immunodeficiency viruses
       (HIV) types 1 and 2 are members. We attempt to describe how retroviruses
       work, particularly HIV-1, and what regulates their expression in the
       host-cell system. Viral stability and its implications for health care
       workers is also discussed. One of the many mysteries of HIV is the
       ability it has to elude normal immune responses. Even though B- and
       T-cell responses are mounted by people infected with HIV, such responses
       are restricted and increasingly ineffective as the disease progresses.
       Host susceptibility plays a major role in the virus' ability to infect
       individuals. Finally, some current treatment options and the key role of
       the family physician in the battle against acquired immunodeficiency
       syndrome are discussed.
 DE    Acquired Immunodeficiency Syndrome/*MICROBIOLOGY  Human
       HIV-1/*PHYSIOLOGY  JOURNAL ARTICLE  REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

