       Document 0441
 DOCN  M9460441
 TI    A patient with anaplastic large cell lymphoma (Ki-1 lymphoma) showing
       clonal integration of HTLV-1 proviral DNA.
 DT    9404
 AU    Takimoto Y; Tanaka H; Tanabe O; Kuramoto A; Sasaki N; Nanba K;
       Department of Internal Medicine, Hiroshima University, Japan.
 SO    Leukemia. 1994 Mar;8(3):507-9. Unique Identifier : AIDSLINE MED/94173104
 AB    We encountered a patient with anaplastic large cell lymphoma (Ki-1
       lymphoma) that originated in the stomach and showed histiocytic
       lymphoma-like morphology. CD43 antigen was positive, and rearrangement
       of TCR-beta gene was observed. The lymphoma was the T-cell type. Though
       no atypical lymphocytes or histological images specific to adult T-cell
       leukemia were observed, clonal integration of HTLV-1 proviral DNA was
       noted. Viruses such as HTLV-1 appear to be involved in the development
       of some anaplastic large cell lymphomas.
 DE    Adult  Case Report  DNA, Viral/*ANALYSIS  Gene Rearrangement, beta-Chain
       T-Cell Antigen Receptor  Human  HTLV-I Antibodies/ANALYSIS  Lymphoma,
       Large-Cell, Ki-1/*GENETICS/MICROBIOLOGY/PATHOLOGY  Male  Stomach
       Neoplasms/*GENETICS/MICROBIOLOGY/PATHOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

