       Document 0404
 DOCN  M9460404
 TI    Simplified exercise test for the initial differential diagnosis of
       Pneumocystis carinii pneumonia in HIV antibody positive patients.
 DT    9404
 AU    Sauleda J; Gea J; Aran X; Aguar MC; Orozco-Levi M; Broquetas JM; Servei
       de Pneumologia, Hospital del Mar, Barcelona, Spain.
 SO    Thorax. 1994 Feb;49(2):112-4. Unique Identifier : AIDSLINE MED/94174465
 AB    BACKGROUND--This study was designed to evaluate the usefulness of a
       simplified exercise test in the differential diagnosis of Pneumocystis
       carinii pneumonia (PCP). METHODS--Forty five subjects with antibodies
       against the human immunodeficiency virus (HIV) and pneumonia were
       included and divided into two groups: those with PCP and those with
       other pneumonias (non-PCP). The test involved pedalling for two minutes
       on a stretcher bed and was considered positive if SaO2 decreased by at
       least 3%. RESULTS--During the exercise the mean(SE) SaO2 fell in
       patients with PCP from 88(4)% to 84(3)%, p < 0.01, whilst it improved
       slightly in subjects with non-PCP from 91(1)% to 93(3)%, p < 0.05.
       Sensitivity was 77% and specificity 91%. CONCLUSIONS--This simple test
       seems potentially useful for the initial investigation of HIV antibody
       positive patients with pneumonia.
 DE    Adult  Comparative Study  Diagnosis, Differential  Exercise
       Test/*METHODS  Human  HIV Seropositivity/BLOOD/*COMPLICATIONS
       Oxygen/BLOOD  Pneumonia/BLOOD/DIAGNOSIS  Pneumonia, Pneumocystis
       carinii/BLOOD/COMPLICATIONS/*DIAGNOSIS  Support, Non-U.S. Gov't  JOURNAL
       ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

