       Document 0388
 DOCN  M9460388
 TI    Nucleotide sequence analysis of HTLV-I isolate from a Korean patient
       with HAM/TSP.
 DT    9404
 AU    Saito M; Moritoyo T; Park JH; Lee BI; Kim JS; Fujisawa J; Osame M;
       Yoshida M; Department of Cellular and Molecular Biology, University of;
       Tokyo, Japan.
 SO    Yonsei Med J. 1993 Dec;34(4):321-7. Unique Identifier : AIDSLINE
       MED/94174841
 AB    Limited nucleotide sequences of human T-cell lymphotropic virus type I
       (HTLV-1) provirus isolated from the first case of a Korean patient with
       HTLV-I associated myelopathy and tropical spastic paraparesis (HAM/TSP)
       were analysed and compared with other isolates from different regions of
       the world. The sequences of the env, LTR regions (536bp, 690bp
       respectively) showed 98.7%, 99.3% homologies with the prototype HTLV-I,
       ATK-1, isolated from a Japanese Adult T-cell leukemia (ATL) patient. A
       comparison between other isolates from different geographical origins
       revealed that the Korean HTLV-I isolate is more closely related to
       Japanese isolates than to those from other geographical origins.
 DE    Adult  Base Sequence  Case Report  DNA, Viral/GENETICS  Human
       HTLV-I/*GENETICS/ISOLATION & PURIF  Korea/ETHNOLOGY  Male  Molecular
       Probes/GENETICS  Molecular Sequence Data  Paraparesis, Tropical
       Spastic/ETHNOLOGY/EPIDEMIOLOGY/*GENETICS/  *MICROBIOLOGY  JOURNAL
       ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

