       Document 0187
 DOCN  M9460187
 TI    Accuracy and cost-effectiveness of a one-tube, three-color method for
       obtaining absolute CD4 counts and CD4:CD8 ratios.
 DT    9404
 AU    McCoy JP Jr; Blumstein L; Donaldson MH; Baxter JD; Byrne BC; Gekowski
       KM; Division of Pediatric Hematology and Oncology, Cooper; Hospital/UMC,
       University of Medicine and Dentistry of New; Jersey-Robert Wood Johnson
       Medical School at Camden.
 SO    Am J Clin Pathol. 1994 Mar;101(3):279-82. Unique Identifier : AIDSLINE
       MED/94182535
 AB    An increasing number of assays to determine absolute CD4 counts are
       being performed as the acquired immunodeficiency syndrome epidemic
       continues. Simultaneously, there is increasing pressure to contain costs
       in the clinical laboratory. A rapid, one-tube, three-color method for
       obtaining CD4 counts has been evaluated for accuracy, compared with a
       more traditional two-color panel of markers. The data, compiled on 102
       patients, including both pediatric and adult human immunodeficiency
       virus-infected patients, indicate a high degree of correlation between
       the one-tube method and a traditional panel. This approach should be
       considered for cost-effective and accurate CD4 determinations.
 DE    Adult  Child  Comparative Study  Cost-Benefit Analysis  *CD4-CD8 Ratio
       Female  Human  HIV Infections/*BLOOD  Leukocyte
       Count/*ECONOMICS/*METHODS  Male  Reproducibility of Results  *T4
       Lymphocytes  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

