






             HGMP-RC - UK Human Genome Mapping Project Resource Centre


            _A_d_d_r_e_s_s:
               UK HGMP Resource Centre
               Clinical Research Centre
               Watford Road
               Harrow MIDDX HA1 3UJ
               United Kingdom

            _E_m_a_i_l: c.bates@CRC.AC.UK

            _P_h_o_n_e: + 44 81 3466
               FAX: + 44 81 869 3807

            _D_e_s_c_r_i_p_t_i_o_n

            In 1990, the UK Medical Research Council (MRC)  founded,  as
            part of the UK Human Genome Mapping Project, a Resource Cen-
            tre (HGMP-RC) at the Clinical Research Centre (CRC), Harrow,
            Middlesex.   The  objectives of the HGMP-RC computing are to
            establish and make available  databases  of  genes,  genetic
            markers  and  map  locations,  and  to develop new computing
            environments and methods for  acquisition  and  analysis  of
            such   data.    Computing  and  networking  facilities  were
            developed by the MRC to provide online computing support  to
            the Project.

            The facilities are connected to a number of other  computing
            systems   in  centres  of  genetics  and  molecular  biology
            research excellence worldwide through national and  interna-
            tional  wide  area  networks  (WAN's) including the European
            Research Backbone Network  (EBONE),  INTERNET,  Public  Data
            Networks  (Packet  Switching  and  Telephone)  in the UK and
            overseas, research and academic networks in the UK and over-
            seas,  European  Molecular Biology Network (EMBNet) and oth-
            ers. Direct connectivity to US laboratories was  implemented
            using a high-speed communication link, the UK-US 'fat pipe'.

            A great deal of effort has been spent on improving  services
            to  the scientific community.  Molecular genetics databases,
            application  software   and   miscellaneous   services   are
            _________________________
            The information in this section is provided  in  accor-
            dance  with the copyright notice appearing at the front
            of this guide.




            August 29, 1992             NNSC       Section 5.48,  Page 1








            available on the HGMP computer  systems  and  other  systems
            around  the  world  through  the  HGMP-RC  Menu system using
            workstations, personal computers or terminals from number of
            manufacturers,  equipped  with  appropriate  networking  and
            graphical facilities and  connected  to  any  of  the  above
            WAN's.

            _N_e_t_w_o_r_k _A_c_c_e_s_s

            The HGMP-RC computing facilities  can  be  accessed  in  two
            ways:

            o+  by using the IP (Internet Protocol) service

            o+  by  making   an   X29   call,   using   a   PAD   (packet
               assembler/disassembler)

            _W_h_o _C_a_n _U_s_e _t_h_e _U_K _H_G_M_P-_R_C _F_a_c_i_l_i_t_i_e_s

            Registration is open, subject to the rules of HGMP,  to  any
            "bona fide" academic who applies, whether based in the UK or
            elsewhere.  To register as  a  UK  HGMP-RC  facilities  user
            please  contact  the  address  above  (email is not used for
            registration applications).

            _R_e_f_e_r_e_n_c_e_s

            For a detailed description of the system and services avail-
            able  see  Rysavy,  F.R.,Bishop,  M.J. at al., "The UK Human
            Genome Mapping Project online computing service."  "Computer
            Applications  in the Biosciences", Vol.8, no.2. 1992 , Pages
            149-154. Several user manuals describing the  usage  of  the
            HGMP-RC  computing  facilities  have  been  written  and are
            available to registered users.  The  user  support  desk  is
            maintained  during  working  hours, providing practical help
            with users' problems.  A programme of courses aimed at  giv-
            ing  an understanding of what the facilities can provide are
            run regularly.













            August 29, 1992             NNSC       Section 5.48,  Page 2


